陀螺旋转式钴60放射外科治疗系统治疗腹膜后淋巴结转移瘤的近期疗效观察

Clinical Observation of Treatment of Retroperitoneal Lymph Node Metastasis by the Radiation Therapy of Gyro Rotary 60 Cobalt Radiation Treatment System

目的探讨陀螺旋转式钴60放射外科治疗系统治疗腹膜后淋巴结转移瘤的近期疗效。方法32例腹膜后淋巴结转移患者，给予陀螺旋转式钴60放射外科治疗系统治疗，50％-70％等剂量曲线覆盖整个靶区，单次周边剂量给予3-5Gy，周边总剂量35-50Gy。结果32例中完全缓解（CR）24例，部分缓解（PR）7例，无变化（SD）1例。总有效率（CR＋PR）为97．0％．多因素分析显示原发病、放疗剂量、症状缓解影响预后，而淋巴结转移大小、是否有癌栓、放疗体积与预后无关。结论陀螺旋转式钴60放射外科治疗系统（简称陀螺刀）治疗腹膜后淋巴结转移瘤安全有效，可作为腹膜后淋巴结转移瘤的辅助性治疗手段。

Objective To analyze the clinical observation of treatment of retroperitoneal lymph node metas- tasis by the radiation therapy of gyro rotary 60 cobah radiation treatment system. Methods Thirty two patients with retro- peritoneal lymph node metastasis were treated with stereotactic radiotherapy in our department. The dose was 3 -5Gy per fraction,the total dose of retroperitoneal were ranged from 35Gy to 50Gy, five times a week. The planned target volume was encompassed by more than 50% to 70% isodose line. Results The overall response rate（ CR ＋ PR） was 97.0%. Multivariate analysis showed that original illness,radiotherapy dose and partial and complete response were related to i- dentil＇led predictors of outcome, and the volume of radiotherapy, the size of metastatic-lymph node and tumor thrombi were not related to the outcome. Conclusion The radiation therapy of gyro rotary 60 cobalt radiation treatment system is a safe and effective treatment tor retroperitoneal lymph node metastasis. It can be used as adjuvant therapy with the radia- tion therapy of gyro rotary 60 cobalt radiation treatment system.