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头皮屑与角质层功能障碍第二部分:角质层与头皮屑 被引量:8

Stratum corneum dysfunction in dandruff Part2:Stratum corneum and dandruff
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摘要 健康角质层形成了一层保护屏障,防止头皮水分散失并保湿,同时保护头皮不受外界损伤(如包括马拉色菌在内的微生物或者有毒物质)。严重的或慢性的屏障损伤会减少应有的水分从而导致非典型的表皮细胞增殖、角化细胞分化及成熟.从而引起头皮屑症状的产生。头皮屑人群的头皮角质层中结构脂质缺失、无序排列,与高经皮水分丢失所表征的头皮屏障脆弱状态相一致。头皮屑人群头皮屏障功能脆弱的证据包括亚临床炎症和对局部刺激的高敏感性。
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2013年第7期442-445,共4页 Journal of Clinical Dermatology
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