磷酸奥司他韦联合板蓝根颗粒治疗甲型H1N1流感疗效观察

Efficacy of treatment of influenza A ( H1N1) with oseltamivir phosphate and isatis root granules

目的观察磷酸奥司他韦联合板蓝根颗粒治疗甲型H1N1流感的临床疗效。方法以我院收治的235例甲型H1N1流感患者为研究对象,随机分为实验组和对照组,其中实验组128例,应用磷酸奥司他韦联合板蓝根颗粒治疗;对照组107例,单用磷酸奥司他韦治疗。对比2组的热程、临床症状、血常规、病毒学检验、住院天数等,从而评价疗效差异。结果入院治疗第3天时,实验组在体温、咳嗽、咳痰、咽痛等临床表现恢复方面均好于对照组(P<0.05);实验组平均住院天数(5.18±3.77)d明显少于对照组平均住院天数(7.86±5.43)d(P<0.05)。结论磷酸奥司他韦联合板蓝根治疗甲型H1N1流感临床疗效明显优于单用磷酸奥司他韦。

Objective To observe the efficacy of the treatment of influenza A （ H1 N1 ） with Oseltamivir phosphate and ban-langen granules. Methods 235 in - patients who were diagnosed as having influenza A （ H1 N1 ） were divided into trial group and control group. The trial group including 128 patients was administered with oseltamivir phosphate and isatis root granules, and the con-trol group including 107 patients was administered with oseltamivir phosphate only. The temperature period, clinical symptoms, blood routine, viral test and length of stay were compared between the 2 groups. Results After 3 days of treatment, recovery of symptoms including temperature, cough, expectoration and throat sore in the trial group was significantly better than that in control group （ P 〈 0.05 ）. The length of stay in the trial group （5.18 ＋ 3.77 d） was significantly shorter than that in the control group （7.86 ± 5.43 d） （ P 〈 0.05 ）. Conclusions The clinical efficacy of treatment of influenza A （ H1 N1 ） with oseltamivir phosphate and isatis root gran-ules is better than that using oseltamivir phosphate only.