冠心病心绞痛患者中医证型与生存质量相关性

Correlation Between TCM Syndrome of Patients with Angina Pectoris and Quality of Life

目的:探讨冠心病稳定型心绞痛患者中医不同证型与生存质量的关系。方法:采用横断面调查方法,一次性采集多个分中心符合入选标准的1788例患者,使用西雅图心绞痛量表(SAQ)作为评价生存质量的工具,运用Logistic回归、单因素方差分析,探讨SAQ5个不同维度得分及总分与冠心病稳定型心绞痛患者中医证型的关系。结果:冠心病稳定型心绞痛患者生存质量的5个维度得分不同,其中治疗满意度平均分最高,躯体活动受限程度平均分最低。不同维度下的三组间生命质量的差异均无统计学意义,即P>0.05。痰瘀互结组与心绞痛发作频率维度关系最密切成负相关,气虚血瘀组与心绞痛稳定状态维度关系最密切成正相关。结论:冠心病稳定型心绞痛患者不同证型与生存质量间存在一定相关性,并且结果符合中医理论的内涵。

Objective：To study the correlation between different syndromes of traditional Chinese medicine （ TCM ） and quality of life （ QOL ） of the patients with angina pectoris. Methods ： With the cross- sectional survey method, 1788 patients with angina pectoris confirmed by coronary angiography ＇were collected at the same time, and their QOL was assessed by the Seattle Angina Questionnaires＇（ SAQ ）. The correlation of the scores of five different dimensions, including somatic movement limitation,j ,angina stability and attacks, angina frequency, treatment satisfaction, and disease recognition, and the total scores of SAQ and the TCM syndromes were analyzed by Logistic regression and single factor analysis of variance. Results ： Five dimensions＇ scores of the quality of life in coronary heart disease in patients with stable angina pectoris were different, in which the scores of treatment satisfaction was the highest and the scores of somatic movement limitation were the lowest.Under different dimensions, there was no significant idifferenee of the QOL among three groups statistically, P〉0.05.Phlegm and blood stasis group and angina ~requency dimension had negative relationship and Qi deficiency and blood stasis group and angina stability and attacks dimension had closely positive correlation. Conclusion ： There was a correlation betweelhe TCM . syndromes and the QOL of the patients with angina pectoris, and the result is in line with the connotation of the traditional Chinese medicine theory.