摘要
试验研究了藤茶中二氢杨梅素对预防大鼠肾结石的作用机制。结果表明:二氢杨梅素能够降低大鼠血清BUN、Cr和尿中Ca、UA含量,增加肾组织SOD活性,降低MDA含量。肾组织切片显示,二氢杨梅素组草酸钙结晶明显减少,管腔扩张减小,说明二氢杨梅素对大鼠肾结石有一定的防治作用。
The prevention mechanism of dihydromyricerin in Ampelopsis grossedentata on rat kidney stones was studied in the current work. The results showed that the concentrations of BUN or Cr in serum, and Ca or UA in urine were reduced, while SOD activity in renal tissue was increased. MDA content was also decreased by dihydromyricetin. Renal biopsy revealed that the calcium oxalate crystals of rat in dihydromyricetin group were significantly reduced, and the lumen expansion was also decreased. Therefore, dihydromyricetin had a preventive effect on rat kidney stones.
出处
《山地农业生物学报》
2013年第3期247-250,共4页
Journal of Mountain Agriculture and Biology
基金
贵州省科技厅农业攻关项目"贵州藤茶黄酮提取及抗结石
祛斑药理作用研究"[黔科合NY(2011)3094号]
贵州藤茶资源及深加工技术研究与应用[黔科合人才团队(2010)4008]
贵阳市科技计划项目2012大学生科技创业计划"中兽药研发科技创新人才团队"[筑科合同(2012)4-7号]
关键词
藤茶
二氢杨梅素
肾结石
草酸钙
Ampelopsis grossedentata
Dihydromyricetin
Kidney stones
Calcium oxalate
