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血清HMGB1、MIF、IL-6水平在川崎病患儿中的临床意义 被引量：7

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摘要 川崎病（Kawasaki Disease,KD）是一种好发于5岁以下儿童的全身性非特异性血管炎。本病在世界范围内均有发现,以亚洲地区发病率最高。其病变主要累及冠状动脉,若未经治疗,20%-25%的患儿发生冠状动脉损伤（coronary artery lesion,CAL）或冠状动脉瘤[1],由于KD临床表现不典型、
作者 李艳飞 金莲花 杨思睿 朴金花
机构地区 吉林大学白求恩第一医院
出处 《中国实验诊断学》 2013年第6期1087-1090,共4页 Chinese Journal of Laboratory Diagnosis
基金 吉林省卫生厅科研课题(2009S013)
关键词 川崎病 HMGB1 临床意义 IL-6 患儿 MIF 冠状动脉损伤 临床表现不典型
分类号 R725.4 [医药卫生—儿科]
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参考文献20

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二级参考文献54

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共引文献28

同被引文献56

  • 1常健,鲁继荣,梁东,李海波,陈银波,赵红霞.川崎病患儿急性期Th1/Th2细胞功能状态的研究[J].中华儿科杂志,2006,44(5):377-378. 被引量：8
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  • 4Newburger JW, Takahashi M, Gerber MA, et a]. Diagnosis, treat- ment, and long - term management of Kawasaki disease: a state- ment for health professionals from the Committee on Rheumatic Fe- ver, Endocarditis, and Kawasaki Disease, Council on Cardiovas- cular Disease in the Young, American Heart Association [ J ]. Cir- culation, 2004, 110 ( 17 ) : 2747 - 2771.
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  • 6KobashiY, ShimizuH, OhueY, et al.Comparison of T-cell interferon-gamma release assays for Mycobacterium tuberculosis-specific antigens in patients with active and latent tuberculosis.Lung, 2010, 188(4):283-287.DOI:10.1007/s00408-010-9238-3.
  • 7马春燕.HMGB1及其受体RAGE在系统性红斑狼疮发病中的作用研究.济南:山东大学,2011.
  • 8YabeH, OhshimaH, TakanoY, et al.Mucosal lesions may be a minor complication of SAPHO syndrome: a study of 11 Japanese patients with SAPHO syndrome. Rheumatol Int, 2010, 30(10):1277-1283.DOI:10.1007/s00296-009-1138-6.
  • 9KaurS, KulkarniKP, DubeyPN.Facial palsy in a 2-month-old infant with Kawasaki disease. Rheumatol Int, 2010, 30(10):1407-1408.DOI: 10.1007/s00296-009-1174-2.
  • 10尹薇,熊俊惠,刘亚黎,刘玲,彭华.核因子-κB信号途径活化对川崎病冠状动脉损害作用的研究[J].中国实用儿科杂志,2008,23(6):433-435. 被引量：11

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中国实验诊断学
2013年 第6期

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