植物脂质转运蛋白的研究进展

Progress in the Studies of Lipid-transfer Protein.

高等植物脂质转运蛋白 (lipid transferproteins ,LTP)是一类小分子 (约 9ku)的碱性蛋白质 ,已从多种植物中纯化出了LTP ,且编码LTP的cDNA及基因也从不同植物中克隆 .LTP能够在生物膜之间转运磷脂 ,因而认为LTP参与了细胞内生物膜形成 .而近期的研究又发现LTP具信号肽 ,可从细胞内分泌到细胞外 ,位于细胞壁上 ,因而又对其在细胞内的转运脂质能力产生疑问 .而有证据表明LTP参与了角质与腊质的形成、植物的抗病反应和植物对环境变化 (温度、盐、干旱协迫 )

Lipid transfer proteins(LTPs) are a group of basic, small (9 ku) proteins which transfer lipids between biomembranes by in vitro assays. So they are thought to participate in the lipid transferring during biomembrane synthesis . Their purification, structure, gene expression and biological functions have been studied in various monocotyledonous and dicotyledonous plants. The latest studies found that they are secreted and located in the cell wall, and that it is suggested that plant LTPs are possibly related with cutin formation, defense reactions against phytopathogens and plant adaptation to various environmental stresses.