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β受体阻滞剂与慢性阻塞性肺疾病

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摘要 随着年龄的增加,慢性阻塞性肺疾病(COPD)和冠心病发病率和病死率增加。尽管有β受体阻滞剂(BBs)疗效的明确证据,但该类药物在COPD患者中的应用目前仍存在广泛的争议。争议的原因在于潜在的禁忌证及害怕导致不良反应和气管痉挛。越来越多来自于临床试验和荟萃分析的证据表明:BBs在心脏疾病患者和伴随COPD患者中耐受性良好;反应性气道疾病患者或者COPD患者不应该拒绝BBs使用。在本文中,我们将讨论COPD患者中BBs的应用及安全性。
作者 黄四春 郭毅
出处 《广东医学》 CAS CSCD 北大核心 2013年第12期1936-1938,共3页 Guangdong Medical Journal
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