β受体阻滞剂与慢性阻塞性肺疾病
摘要
随着年龄的增加,慢性阻塞性肺疾病(COPD)和冠心病发病率和病死率增加。尽管有β受体阻滞剂(BBs)疗效的明确证据,但该类药物在COPD患者中的应用目前仍存在广泛的争议。争议的原因在于潜在的禁忌证及害怕导致不良反应和气管痉挛。越来越多来自于临床试验和荟萃分析的证据表明:BBs在心脏疾病患者和伴随COPD患者中耐受性良好;反应性气道疾病患者或者COPD患者不应该拒绝BBs使用。在本文中,我们将讨论COPD患者中BBs的应用及安全性。
出处
《广东医学》
CAS
CSCD
北大核心
2013年第12期1936-1938,共3页
Guangdong Medical Journal
参考文献18
-
1KALINOWSKI L, DOBRUCHI L W, SZCZEPANSKA KONKEL M, et al. Thirdgeneration beta - blockers stimulate nitric oxide re- lease from endothelial cells through ATP efflux: a novel mecha- nism for antihypertensive action [ J ]. Circulation, 2003, 107 (21) : 2747 -2752.
-
2WELLSTEIN A, PALM D, BELZ G G, et al. Reduction of exer- cise tachycardia in man after propranolol, atenolol, bisoprolol in comarison to beta - adrenoceptor occupancy [ J ]. Eur Heart J, 1987, 8:3-8.
-
3WRIGHT R S, ANDERSON J L, ADAMS C D, et al. 2011 AC- CF/AHA focused update incorporated into the ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/ Non - ST - Elevation Myocardial Infarction : a report of the Ameri- can College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the American Academy of Family Physicians, Society for Cardio- vascular Angiography and Interventions, and the Society of Tho- racic Surgeons[ J]. J Am Call Cardiol, 2011, 57 (19) : e215 - e367.
-
4SIN D D, MAN S F. Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases.'? The potential role of systemic inflammation in chronic obstructive pulmonary disease[ J]. Circulation, 2003, 107 ( 11 ) : 1514 - 1519.
-
5GAULD D R, PAIN M C, RUBINFELD A R. Beta- blocking drugs and airways obstruction[ J]. Med J Aust, 1979, 2(2) : 88.
-
6PAINE J M, PALAZZO M G, KERR J H, et ol. Near -fatal bronehospasm after oral nadolol in a young asthmatic and response to ventilation with halothane[ J]. Br Med J(Clin Res Ed), 1981, 282 (6263) : 548 - 549.
-
7WILLIAMS I P, MILLARD F J. Severe asthma after inadvertent ingestion of oxprenolol[J]. Thorax, 1980, 35(2) : 160.
-
8EGRED M, SHAW S, MOHAMMAD B, et al. Under - use of be- ta - blockers in patients with ischaemic heart disease and concomi- tant chronic obstructive pulmonary disease [ J ]. QJM, 2005, 98 (7) : 493 - 497.
-
9AGUSTI A, CALVERLEY P M, CELLI B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort [ J]. Respir Res, 2010, 11: 122.
-
10ZVEZDIN B, MILUTINOV S, KOJICIC M, et al. A postmortemanalysis of major causes of early death in patients hospitalized with COPD exacerbation[J]. Chest, 2009, 136(2): 376-380.
-
1陈青梅,孙一娜,骆梅,庞美芳.急性有机磷农药中毒患者的急诊抢救和护理体会[J].广东医学院学报,2004,22(6):615-615.
-
2邓活,翁海贞.甲亢术并发气管痉挛5例的抢救体会[J].广东医学院学报,1996,14(1):67-68.
-
3王洁.甲状腺术后并发气管痉挛对急救护理的启示[J].护理学杂志(综合版),1997,12(5):299-300. 被引量:1
-
4李兆民,张士成,费峰.卡托普利与硝苯地平联合应用治疗高血压病疗效观察[J].黑龙江医学,1998,0(8):30-31. 被引量:1
-
5王萍.急性有机磷农药中毒34例护理体会[J].临床合理用药杂志,2014,7(5):147-148. 被引量:1
-
6任尚秀,宛江鹤.有机磷农药中毒的临床观察及护理[J].现代中西医结合杂志,2003,12(3):324-325.
-
7陈义芳.急性有机磷中毒病人的临床观察及护理[J].遵义科技,2004,32(2):45-45.
-
8李彦玲,宋世娥.急性有机磷农药中毒的急救与护理[J].中华当代医学,2006,4(4):99-99.
-
9马德奎,黄擎雄,吴志扬,冯平,彭和平,任朝林.甲状腺疾病围手术期伴发气管痉挛28例分析[J].新乡医学院学报,2007,24(1):91-92. 被引量:3
-
10阳淑芳.糖皮质激素在支气管哮喘患者中的应用及安全性研究[J].现代诊断与治疗,2016,27(18):3377-3378.