期刊文献+

血管内皮生长因子C在肿瘤中的作用

下载PDF
导出
摘要 血管内皮生长因子(VEGF)是血管内皮细胞特异的分裂原,能特异地刺激内皮细胞分裂与增殖,促进血管的生长。VEGF-C是VEGF家族中的一员。许多研究结果表明在肿瘤组织中可见肿瘤周边新生的淋巴管、扩张的淋巴管、有癌栓的淋巴管和有肿瘤转移的淋巴结内淋巴管内皮细胞的血管内皮生长因子受体3(VEGFR-3)呈高表达,
出处 《广东医学》 CAS CSCD 北大核心 2013年第12期1943-1945,共3页 Guangdong Medical Journal
  • 相关文献

参考文献25

  • 1CHENG H T, HUNG W C. Inhibition of lymphangiogenic factor VEGF - C expression and production by the histone deacetylase in- hibitor suberoylanilide hydroxamic acid in breast cancer cells [ J ]. Oncol Rep, 2013, 29(3) : 1238 -1244.
  • 2MANDRIOTA S J, JUSSILA L, JELTSCH M, et al. Vascular en- dothelial growth factor - C - mediated lymphangiogenesis promotes tumour metastasis[J]. EMBO J, 2001,20(4) : 672 -682.
  • 3张广军,王子安.VEGF-C、VEGFR-3生物学机制和在肿瘤研究中的进展[J].中华全科医学,2010,8(3):368-370. 被引量:12
  • 4LIU B, MA J, WANG X, et al. Lymphangiogenesis and its rela- tionship with lymphatic metastasis and prognosis in malignant mela- noma[ J~. Anat Rec ( Hoboken), 2008, 291 (10) : 1227 - 1235.
  • 5杨树才,杨明光,李鑫磊,马晶,张雅芳.VEGF-C表达与胰腺癌淋巴结转移及预后的关系[J].解剖科学进展,2012,18(5):419-422. 被引量:2
  • 6WANG Z, CHEN Y, LI X, et al. Expression of VEGF - C/VEG- FR -3 in human laryngeal squamous cell carcinomas and its signifi~ cance for lymphatic metastasis [ J ]. Asian Pac J Cancer Prey, 2012, 13(1) : 27 -31.
  • 7LI X, DANG X, SUN X. Expression of survivin and VEGF - C in breast cancer tissue and its relation to lymphatic metastasis [ J ]. Eur J Gynaecol Oncol, 2012, 33(2) : 178 -182.
  • 8ZHAO Y C, NIX J, WANG M H, et al. Tumor - derived VEGF - C, but not VEGF - D, promotes sentinel lymph node lymphangio- genesis prior to metastasis in breast cancer patients [ J ]. Med On- col, 2012, 29(4) : 2594 -2600.
  • 9WAKISAKA N, HIROTA K, KONDO S, et al. Induction of lym- phangiogenesis through vascular endothelial growth factor - C/vas- cular endothelial growth factor receptor 3 axis and its correlation with lymph node metastasis in nasopharyngeal carcinoma[ J]. Oral Oncol, 2012, 48(8) : 703 -708.
  • 10LI X, LIU B, XIAO J, et al. Roles of VEGF - C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in co- lon cancer[J]. J Gastrointest Surg, 2011, 15 ( 11 ) : 2001 - 2010.

二级参考文献41

  • 1刘进,薛新波.P53、VEGF和VEGF-C在胰腺癌中的表达及意义[J].华中科技大学学报(医学版),2004,33(4):472-474. 被引量:7
  • 2张孝艳,乔玉环,史惠蓉.VEGF-C与妇科肿瘤关系的研究进展[J].国外医学(妇产科学分册),2005,32(3):180-183. 被引量:1
  • 3马凤江,智绪亭.血管内皮生长因子-C在胃癌组织中的表达及与肿瘤淋巴结转移的关系[J].肿瘤防治杂志,2005,12(4):281-282. 被引量:12
  • 4Kaipainen A, Korhonen J, Mustonen T, et al. Expression of the like tyrosine gene become to lymphatic endothelium during development [J]. Proc Nati Acad Sci USA, 1995,92(8) :1599 - 1604
  • 5Agnes Fetal. Genomic organization of the extra cellular coding region of the human VEGF and FLT4 genes: evolution of the genes encoding receptor tyrosine with immunoglobulin-like domains[J]. J Mol, 1997,45:432
  • 6Van Trappen, Steele D, Lowe DG, et al. Expression of vascular endothelial growth factor (VEGF) - C and VEGF - D and their receptor VEGFR - 3, during different stages of cervical carcinogenesis[J]. J Pat,2003,201(4) :544 - 554
  • 7Oh SL,Jeltsch MM,Birkenhager R,et al. VEGF and VEGF- C: specific induction of angiogenesis and lymph angiogenesis in the differentiated avian membrane[J]. Dev Bio,1997,188(1) :96 - 109
  • 8Jeltsch M, Kaipainen A, Joukov V, et al. Hyperplasia of lymphatic vessels in VEGF - C transgenic mouse [ J ]. Science ( Washington DC), 1997,276(5317) : 1423 - 1425
  • 9Skobe M, Hamberg LM, Hawighorst T, et al. Concurrent induction of lymph angiogenesis, and macrophage recruitment by vascular endothelial growth factor C in melanoma[J]. Am J Path, 2001,159 (3) :893 - 903
  • 10Yanai Y, Furuhata T, Kimura Y, et al. Vascular endothelial growth factor C promotes human gastric carcinoma lymph node metastasis in mice[J]. J Cancer,2001,20(3) :419 - 428

共引文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部