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辛伐他汀对急性心肌梗死的疗效及血脂水平的影响 被引量:1

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摘要 目的探讨辛伐他汀治疗急性心肌梗死的疗效和对患者血脂水平的影响。方法选取2010年6月至2012年6月收治的急性心肌梗死患者95例,分为对照组和观察组,对照组43例给予溶栓、抗凝、抗心力衰竭等常规治疗,观察组52例在常规治疗的基础上睡前给予辛伐他汀20 mg/d。4周后比较两组治疗效果、血脂、主要心脏不良事件发生率及药物不良反应。结果两组总有效率分别为79.07%和92.31%,观察组明显高于对照组(P<0.05)。与治疗前比较,两组治疗后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)明显下降,高密度脂蛋白胆固醇(HDL-C)明显升高(P<0.05),观察组改善更显著(P<0.05)。观察组患者主要心脏不良反应发生率较对照组明显降低(P<0.05)。两组不良反应比较无统计学意义(P>0.05)。结论辛伐他汀治疗急性心肌梗死,可显著改善患者血脂水平,降低心脏不良事件发生率,且不良反应小,值得临床推广。
出处 《中国药业》 CAS 2013年第12期59-61,共3页 China Pharmaceuticals
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