高同型半胱氨酸血症是否干预,如何干预?

Whether and How to Make Interventions to Hyperhomocysteinemia?

高同型半胱氨酸血症是血管阻塞性疾病的独立危险因素,与心脑血管事件的发生密切相关,良好的生活方式与多种药物均可有效降低同型半胱氨酸的水平,其中叶酸与B族维生素起着重要作用。然而也有研究认为采取干预措施未必能真正获益,故是否干预、如何恰当干预高同型半胱氨酸血症仍是目前有争议的问题,有待进一步探讨。本文总结了高同型半胱氨酸血症的干预措施,提醒在目前存在争议的情况下,既要高度重视,更要保持健康的生活方式,以尽可能地避免高同型半胱氨酸血症的出现及减少发生心脑血管事件的风险。

Hyperhomocysteinemia, an independent risk factor for angiemphraxis, is closely related to cardiovascular and cerebrovascular events. Healthy living habits and a list of medicines such as folie acid and B vitamins can reduce the level of homocysteine effectively. However, interventions to hyperhomocysteinemia have been proved, by some studies, to be ineffec- tive. Therefore, whether and how to intervene remains a controversial issue. This article summarizes the intervention measures for hyperhomocysteinemia. Healthy living habits are essential in preventing hyperhomoeysteinemia and cardiovascular, cerebro- vascular events.