30例急性肺血栓栓塞症左心室的结构及功能性改变的临床研究

The structure and functional changes of left ventricle of 30 patients with acute pulmonary thromboembolism

目的探讨急性肺血栓栓塞症左心室的结构和功能的改变情况。方法选取我院2011年1月～2012年12月收治的急性肺血栓栓塞症患者30例为肺血栓栓塞组,选取正常健康者35人为对照组,比较两组IEDVLV、IESVLV、ISV、左室壁厚度和左室面积的差异及血液BNP、cTnI、PaO2的变化。结果与对照组相比,急性肺血栓栓塞后患者的血BNP、cTnI明显增高,动脉PaO2明显减低(P<0.05),急性肺血栓栓塞后患者的左室舒张末容积(IEDVLV)和左室每搏量ISV明显下降,左室壁厚度和左室面积及左室收缩末容积(IESVLV)明显升高,P<0.05,差异具有统计学意义。结论急性肺血栓栓塞症患者的左心室的结构及功能发生明显的损伤。

Objective To discuss the structure and functional changes of left ventricular of patients with acute pul- monary thromboembolism. Methods Selected 30 patients with acute pulmonary thromboembolism in our hospital from January 2011 to December 2012, 35 healthy people as the control, then compared the differences of IEDV_LV, IESV_LV, ISV, the left ventricular, ventricular wall thickness, and the blood BNP, cTnI, PaO2 of the two groups. Results Com- pared with healthy controls, BNP, cTnI in the blood of patients with acute thromboembolism increased significantly, artery PaO2 reduced significantly （P 〈 0.05）, left ventricular end-diastolic volume （IEDVLv） and left ventricular stroke volume ISV obviously declined, and the left ventricular wall thickness and left ventricular size and left ventricular end-systolic volume （IESVLv） increased significantly, P 〈 0.05, the differences were statistically significant. Conclusion Patients with acute pulmonary thromboembolism were with obvious damage of left ventricular structure and function.