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鸡新城疫病毒S_1山东分离株的生物学特性研究

Biological characterization of Newcastle disease virus S_1 strain isolated from laying hens in Shandong
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摘要 通过SPF鸡致病性试验、MDT、ICPI、血凝解脱速率和血凝素热稳定性试验 ,结果表明 ,从山东分离的鸡新城疫病毒S1株与Lasota、F4 8E8间存在生物学差异。对S1株的鸡胚增毒量进行了研究 ,结果显示 ,10 3 5EID50 The low virulent Newcastle disease virus S 1 strain isolated from laying hens in Shandong Province was pathotyped and characterized by challenge with specific pathogen free (SPF) chickens, mean death time (MDT) of embryos, intracerebral pathogenicity index(ICPI), elution rate from chicken erythrocytes and hemagglutinin thermostability The results showed that there were biological differences between NDV-Lasota and F 48 E 8 stain virus In addition, the effect of amount of S 1 strain virus inoculated into 11 day-age SPF embryos on its propagation was determined The data indicated 10 35 EID 50 of seed virus would be optimal and not influence the infectivity of S 1 strain
出处 《山东农业科学》 2000年第3期18-19,共2页 Shandong Agricultural Sciences
关键词 鸡新城疫病毒 弱毒株 生物学特性 MDT ICPI Newcastle disease virus low virulent virus biological characterization
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  • 1国际兽疫局.诊断试验和疫苗标准手册(第三版)[M].,1996..
  • 2陶顺启.亚临床新城疫的流行病学调查&病毒分离鉴定及生物学特性的研究.学位论文[M].南京农业大学,1996..

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