个体化治疗神经外科术后颅内感染25例临床分析

Clinical analysis of individualized treatment in 25 cases of intracranial infection after neurosurgical operations

目的总结神经外科术后颅内感染治疗经验和教训。方法回顾性分析郑州大学第一附属医院神经外科2011年4月至2012年4月收治的25例术后颅内感染患者的临床资料，根据患者具体情况个体化选择性应用静脉用药、皮下积液引流、腰椎穿刺鞘内注射、腰大池或脑室置管外引流、脑室镜下冲洗等多种方法治疗颅内感染并随访3个月。结果20例颅内感染临床治愈，3例放弃治疗，2例死于颅内感染。结论神经外科术后颅内感染应以预防为主，颅内感染后需早期诊断并个体化综合治疗，否则预后极差。本研究方法对治疗神经外科术后颅内感染疗效显著，值得临床推广应用。

Objective To summarize the experiences and lessons from individualized treatment of patients with intracranial infection after neurosurgical operations. Methods The clinical data of 25 patients with postoperative intracranial infection from April 2011 to April 2012 were retrospectively aria-lyzed. A selective variety of treatment methods were provided, such as the administration of intravenous antibiotics, subcutaneous effusion drainage, lumbar puncture and intrathecal injection, continuous lumbar and encephalocele drainage of cerebrospinal fluid and ventricle microscopically ventricle flush. Treatment was provided according to specific circumstance follow-up of three months. Results Twenty patients with intracranial infection were clinically cured, 3 patients refused further treatment, 2 patients died of intracranial infection. Conclusions Prevention is the most important intervention in countering intracranial infection. However, if intracranial infection occures, early diagnosis and effective treatment methods must be provided, otherwise the prognosis is poor. The treatment methods provided are effective and worth popularization.