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重症心衰死亡患者与血乳酸水平的相关性研究 被引量:4

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摘要 目的分析重症心衰患者死亡的发病情况与血乳酸水平的相关性。方法收集住院的心衰死亡患者84例,其中47例(55.5%)发生猝死(A组),37例(44.5%)死于泵衰竭(B组),B组按乳酸水平分为轻度乳酸中毒组(2.1~10.0 mmol/l),重度乳酸中毒组(>10.0 mmol/l),比较两者的住院天数、3天病死率、7天病死率。回顾性分析两组死亡患者的临床资料,包括病史、临床表现、心功能分级、心脏彩超、血乳酸等。结果 A组心功能分级多为Ⅱ、Ⅲ级,左室射血分数高于B组。A组心绞痛发生率高于B组(64%与23%,P<0.05)。B组中乳酸水平越高,趋于死亡时间越短。A组应用他汀类药物及抗血小板聚集药物少于B组。结论心源性猝死多发生在心功能Ⅱ、Ⅲ级的心衰患者。死亡前多伴有心绞痛发作,与应用他汀类药物及抗血小板聚集药物较少有关。且重度乳酸中毒组3天、7天病死率明显高于轻度乳酸中毒组。
出处 《中国现代药物应用》 2013年第13期103-104,共2页 Chinese Journal of Modern Drug Application
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