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胺碘酮联合厄贝沙坦和阿托伐他汀治疗130例阵发性心房颤动患者的临床疗效观察 被引量:12

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摘要 目的观察胺碘酮联合厄贝沙坦、阿托伐他汀治疗阵发性房颤的临床疗效。方法将130例阵发性房颤患者随机分为两组:胺碘酮加阿托伐他汀组(对照组)65例;在对照组用药基础上加用厄贝沙坦组(治疗组)65例。观察两组患者治疗后的窦性心律维持率及治疗前、治疗后6、12、18个月后左心房内径(LA)的变化情况。结果两组治疗后窦性心律维持率均较治疗前显著改善,差异有统计学意义(P<0.05),但组间比较,差异无统计学意义(P>0.05),治疗12个月后治疗组窦性心律维持率明显大于对照组(P<0.05);治疗6个月后两组左心房内径差异无统计学意义,但18个月后治疗组的左心房内径较明显小于对照组(P<0.05)。结论胺碘酮联合厄贝沙坦、阿托伐他汀治疗阵发性心房颤动,其维持窦性心律的疗效优于胺碘酮联合阿托伐他汀,并能延缓左心房的扩大。
出处 《中国现代药物应用》 2013年第13期138-139,共2页 Chinese Journal of Modern Drug Application
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