摘要
二聚西松烷型二萜(biscembranoid)是一类骨架新颖、结构复杂、罕见的海洋天然产物,主要存在于肉芝软珊瑚属珊瑚生物中.这类化合物多具有显著的生物活性,尤其表现为抗炎、抗肿瘤等.对近年来报道的肉芝软珊瑚属中的二聚西松烷型二萜化合物的化学及生物活性进行综述,并对其药用前景作出展望.
Biscembranoides, a kind of novel and complex compounds, mainly exist in the soft corals of the genus sarcophy- ton exhibiting good biological activities in drug discovery, especially for the activities of anti-inflammatory, antitumor, etc. In this review, we focus on the progress in chemical and bioactive research of biscembranoides in recent years and their prospec- tions in the future.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2013年第6期1157-1166,共10页
Chinese Journal of Organic Chemistry
基金
国家海洋"863"计划(Nos.2011AA09070102
2013AA092902)
国家自然科学基金(Nos.81273430
21072204
21021063)
中国科学院国家新药研究重点实验室项目(No.SIMM1203ZZ-03
SIMM1105KF-04)
欧盟第七框架IRSES(2010~2014)资助项目~~