明目地黄丸合生脉散治疗肝肾阴亏型干眼症疗效观察

Clinical Observation of Mingmu Dihuang Pills Plus Shengmai Powder for Treatment of Dry Eye Syndrome

目的:观察明目地黄丸合生脉散治疗肝肾阴亏型干眼症的临床效果。方法:将32例病例随机分为2组,治疗组20例40只眼,用明目地黄丸合生脉散治疗;对照组12例24只眼,予羟糖甘眼液滴眼治疗。结果:总有效率治疗组为97.5%,对照组为66.7%,2组比较,差异有显著性意义(P<0.05)。治疗后治疗组试纸浸湿长度>10mm/5min的病例明显增多,与对照组比较,差异有非常显著性意义(P<0.01)。治疗后治疗组泪膜破裂时间>10s的病例明显增多,与对照组比较,差异有非常显著性意义(P<0.01)。治疗组对泪液分泌量试验、泪膜破裂时间、荧光素染色评分、眼部症状积分的改善均优于对照组(P<0.05)。结论:明目地黄丸合生脉散治疗肝肾阴亏型干眼症效果良好。

Objective： To observe the effect of Mingmu Dihuang pills plus Shengmai powder for the treatment of dry eye syndrome. Methods： A total of 32 cases were randomly divided into treatment group and control group, 20 cases （involving 40 eyes） in the treatment group were treated with Mingmu Dihuang pills and Shengmai powder orally, and 12 cases（involving 24 eyes） in the control group were treated with Tears Naturale（Hypromellose 2910, Dextran 70 and Glycerol Eye Drops）. Results： The total effective rate was 97.5% in the treatment group, and was 66.7% in the control group, the difference being significant（P〈 0.05）. The patients with the length of soaked test paper over 10mm/5min and with the breakup time of tear film over 10s in the treatment group were more than those in the control group（P 〈 0.01）.The treatment group had better effect on Schirmer I test, tear film break-up time, eye symptom score than the control group（P 〈 0.05）. Conclusion： Mingmu Dihuang pills satisfactory effect for the treatment of dry eye syndrome. fluorescent staining score, and plus Shengnmi powder exerts satisfactory effect for the treatment of dry eye syndrome.