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微纳米结构用于人造红细胞的应用研究与进展 被引量：3

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摘要 及时有效的输血是进行生命救治,并维护人体机能正常运转的重要手段,已经广泛应用于临床手术、抗灾和战场救护当中。由于受血液来源、储存及血源性疾病传播等原因的影响,限制了传统输血技术在紧急状况的广泛应用,因此合成可大规模生产的安全有效的血液代用品一直受到研究者的关注。血液主要由血浆和血细胞组成,
作者 李彬 黄宇彬 景遐斌 谢志刚
机构地区 中国科学院长春应用化学研究所高分子物理与化学国家重点实验室
出处 《中国输血杂志》 CAS CSCD 北大核心 2013年第5期420-422,共3页 Chinese Journal of Blood Transfusion
基金 国家自然科学基金委项目(编号20874097) 国家科技部"973"计划(编号2009CB930102) 国家科技部"863"计划(编号2012AA021900) 中国科学院"百人计划"项目(编号KGCX2-YW-802) 吉林省科技厅项目(编号20100588)
关键词 微纳米结构 人造红细胞 血液代用品
分类号 R457.1 [医药卫生—治疗学] R331.141 [医药卫生—人体生理学]
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参考文献36

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二级参考文献10

共引文献19

同被引文献35

  • 1路秀玲.修饰血红蛋白作为红细胞代用品的研究进展和挑战[J].生物工程学报,2006,22(1):7-18. 被引量：11
  • 2刘涛,张贵锋,周卫斌,苏志国.凝胶过滤色谱-多角度激光散射法测定琥珀酰明胶自由氨基修饰度[J].分析化学,2007,35(1):43-48. 被引量：13
  • 3李宁,吴卫星,宋斌.红细胞代用品研发现状和趋势的分析[J].中国输血杂志,2007,20(4):345-348. 被引量：2
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  • 7Zhang N,Palmer AF.Polymerization of human hemoglobin using the crosslinker 1,11-bis(maleimido)triethylene glycol for use as an oxygen carrier.Biotechnology progress,2010,26(5):1481-1485.
  • 8Harrington JP,Wollocko H.Molecular Design Properties of Oxy Vita Hemoglobin,a New Generation Therapeutic Oxygen Carrier:A Review.Journal of Functional Biomaterials,2011,2(4):414-424.
  • 9Zhou Y,Jia Y,Buehler PW,et al.Synthesis,biophysical properties,and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity.Biotechnology progress,2011,27(4):1172-1184.
  • 10Jahr SJ,Akha SA,J Holtby R.Crosslinked,polymerized,and PEGconjugated hemoglobin-based oxygen carriers:clinical safety and efficacy of recent and current products.Current drug discovery technologies,2012,9(3):158-165.

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中国输血杂志
2013年 第5期

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