成人先天性主动脉缩窄临床特征分析

The Analysis of the Clinical Feature of Adult Patients with Coarctation of the Aorta

目的总结成人先天性主动脉缩窄患者的临床特征。资料与方法回顾分析2009年1月至2012年11月在阜外心血管病医院住院治疗的85例年龄大于14岁的先天性主动脉缩窄患者的临床特征。结果平均年龄(25.9±9.9)岁,其中74.1%患者既往有高血压病史,最高血压达到(191.0±26.8/101.7±22.4)mmHg(1mmHg=0.133kPa),合并其他先天性心血管疾病的占69.4%,39.5%的患者接受了外科手术治疗。37.2%的患者接受了介入治疗。结论成人主动脉缩窄患者多因不明原因的高血压而发现,易造成多种高血压并发症,且多合并其他先天性心血管异常,详细的体格检查,测量四肢血压有助于尽早诊断,自然预后差,一旦发现,应尽早进行介入或外科治疗。

Objective Review the clinical features of the adult patients with coarctation of the aorta. Materials and methods 85 adult patients with coarctation of aorta were admitted in Fuwai Hospital from Jan 2009 to Nov 2012. Results The average age was （25.9±9.9） years old. 74.1% patients had histories of hypertention. 69.4% patients were with others congenital cardiovascular diseases. 39.5% patients accepted surgery and 37.2% patients accepted interventional therapy. Conclusion Adult patients with coarctation of the aorta were alwaysfound because of hypertension with unclear reasons, which was prone to leads many complications. Most of them were combined with other congenital cardiovascular disease. Physical examination and measurement of limb blood pressure would be helpful to diagnose. The patients should accept interventional or surgical therapy once they were diagnosed since the poor natural prognosis.