Demirjian法在推断南京地区儿童自然年龄中的应用

Application of Demirjian method in the inference of children's natural age in Nanjing area

目的:研究Demirjian法(下文简称"D法")推断南京地区儿童自然年龄的适用性。方法:收集南京医科大学附属口腔医院符合纳入标准的年龄在3～16岁患者的全口曲面断层片共644例,其中男性378例,女性266例。按照D法进行牙龄推断,所得牙龄与自然年龄进行配对t检验,通过建立单因素数学模型探索两者之间的对应关系。结果:直接运用D法对南京地区儿童进行牙龄推断,所得出的结果与实际年龄相比,差异有统计学意义(P<0.01)。建立南京地区儿童牙齿成熟度与自然年龄间的数学模型,得到自然年龄与牙总成熟度的拟合曲线方程:男子组为Y=43.37SIN(0.02579X-1.138)+30.6SIN(0.04275X+0.9984)+3.019SIN(0.08706X+1.649),女子组为Y=55.93SIN(0.04001X-1.642)+90.97SIN(0.05389X+0.7095)+44.25SIN(0.06254X+3.384)。将其推断的年龄与实际自然年龄比较,两者间的差异无统计学意义(P>0.05)。结论:本研究通过建立儿童牙齿成熟度与自然年龄间的数学模型,可以利用牙齿发育程度较为准确推断南京地区3～16岁儿童的自然年龄。

Objective：To study the applicability of Demirjian＇s method for age estimation in children of Nanjing.Methods：644 panoramic radiographs（ 378 boys and 266 girls） which were collected from Affiliated Hospital of Stomatology of Nanjing Medical University were involved in this study with chronological age from 3 to 16 years.Paired t-test was performed between the chronological age and the age determined by Demirjian＇s method.Single-factor model was used to explore the relationships of the two kinds of age.Results：For the marked difference between the chronological age and determined age（ P 0.01） ,Demirjian＇s method was not suitable to the children in Nanjing.We set up the mathematical model between tooth maturity and natural age of children in Nanjing,then got the curve-fitting equation.For boys：Y = 43.37Sin （ 0.02579X 1.138） ＋ 30.6SIN （ 0.04275X ＋ 0.9984 ） ＋ 3.019SIN （ 0.08706X ＋ 1.649） ,and for girls：Y = 55.93SIN（ 0.04001X 1.642） ＋ 90.97SIN（ 0.05389X ＋ 0.7095） ＋ 44.25SIN（ 0.06254X ＋ 3.384） .The Results of paired t-test between chronological age and predicted age from quadratic equation showed that there was no significant difference in boys and girls（ P 0.05） .Conclusions：Through the establishment of mathematical model between tooth maturity and natural age in this study,we can determine the natural age from 3 to 16 in Nanjing children more accurately by utilizing tooth maturity.