3Nijmeijer S, Leurs R, Vischer H F. Constitutive activity of the hista- mine H( 1 ) receptor[ J ]. Methods Enzymol,2010,484: 127 - 147.
4Mizuguchi H, Ono S, Hattori M, et al. Inverse agonistic activity of anti- histamines and suppression of histamine Hi receptor gene expression [J]. J Pharmacol Sci,2012,118(1) : 117 -21.
5Tanizaki H, Ikoma A, Fukuoka M, et al. Effects of bepotastine and fexofenadine on histamine -induced flare, wheal and itch[ J]. Int Arch Allergy Immunol,2012,158 (2) : 191 - 195.
6Scaglione F. Safety profile of bilastine: 2rid generation H1 - antihista- mines[J]. Eur Rev Med Pharmacol Sci,2012,16(14) : 1999 -2005.