南宁市城区人群人芽囊原虫感染情况调查

Investigation of the prevalence of Blastocystis hominis infection among people in Nanning

目的了解南宁市城区人群人芽囊原虫感染情况及流行规律,为采取相应的防治措施提供科学依据。方法对2009～2011年到医院体检或就诊的4 263例南宁市城区人群进行粪便检查,对人芽囊原虫感染情况进行分析。结果检出人芽囊原虫感染者320例,感染率为7.51%,其中粘液脓血便者的感染率为27.33%(176/644),显著高于其他受检者(χ2=513.2%,P<0.05);单纯人芽囊原虫感染者289例(90.31%),合并华支睾吸虫感染者26例(8.13%);男性感染率为7.72%,女性为7.25%,差异无统计学意义(χ2=0.328,P>0.05);腹泻人群感染率为11.78%,显著高于健康人群感染率(3.56%)(χ2=103.6,P<0.05),但健康人群间感染率差异无统计学意义(χ2=4.561,P>0.05);全年以秋季感染率最高(11.26%),其次是夏季(9.72%);2009～2011年各年度感染率分别为3.86%、7.02%和10.77%,差异有统计学意义(χ2=72.533,P<0.05),感染率呈逐年上升趋势。感染者多有不良卫生、饮食习惯;有症状者229例(71.56%)。结论南宁市城区人群人芽囊原虫感染普遍存在,应全面推进和落实健康教育工作,切断传播途径,以降低人群感染率。

Objective To investigate the prevalence of Blastocystis hominis infection among people in Nanning in order to provide scientific evidence for prevention and control measures. Methods Stool specimens were obtained from 4,263 people undergoing a physical examinations or being seen at this hospital. The prevalence of B. hominis infection was in- vestigated. Results The rate of infection withB, hominis was 7.51% （320/4,263）. The rate of B. hominis infection was much higher among people who had mucopurulent bloody stool （27.33%） than those who did not （176/644;χ^2 = 513.2%, P〈0.05）. Of 320 individuals who were infected, 289 were infected with simple B. hominis （90.31%） and 26 were infected with both B. hominis and Clonorchis sinensis （8. 13%）. The rates of infection did not differ significantly difference males （7.72%） and females （7.25%） （χ^2=0. 328, P：〉0.05）. People with diarrhea had a higher rate of B. hominis infection （11.7%） than healthy individuals （3.56%） （χ^2 =103.6, P〈0.05）, but the difference was not significant （χ^2 =4. 561, P〈0.05）. During the year, the highest rate of infection was in the autumn （11.26%） and then in the summer （9.72% ）. The rate of infection was 3.86% in 2009, 7.02% in 2010, and 10.77% in 2011; the rate of infection each year differed significantly （χ^2= 72. 533, P〈0.05）. Most infected individuals had a poor diet and/or poor hygiene. Of those affected, 229 were symptomatic （71.56%）. Conclusion Infection with B. hominis is prevalent among people in Nanning. Health education will help to block the routes of transmission and reduce the rate of infection.