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不同类型止吐药预防耳鼻喉科手术后恶心呕吐的临床观察

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摘要 目的:观察使用不同类型止吐药防止耳鼻喉科手术后恶心呕吐的疗效,寻求一种理想的止吐药物,预防和减少PONV的发生。方法:择期耳鼻喉科手术患者60例,随机分成(A组)生理盐水对照组,(B组)甲氧氯普胺10mg+地塞米松10 mg,(C组)氟哌利多2.5 mg+地塞米松10 mg,(D组)地塞米松10mg4组,每组各15例。观察术后2 h内、3~6 h、7~24 h各组发生恶心、呕吐的病人数,恶心呕吐的严重程度,头晕头痛、椎体外系症状等副作用发生情况。结果:各组病人性别、年龄、体重、手术持续时间等各组间比较差异无统计学意义(P>0.05)。与A组比较,术后2 h内B组、C组发生恶心、呕吐病人数,PONV严重程度评分均明显降低,差异具有统计学意义(P<0.05)。结论:地塞米松联合甲氧氯普胺和地塞米松联合氟哌利多均能有效地预防耳鼻喉科手术后PONV的发生。
作者 诺明 任志坚
出处 《内蒙古医学杂志》 2013年第4期431-432,共2页 Inner Mongolia Medical Journal
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