疏血通注射液治疗椎动脉型颈椎病的临床疗效观察

Clinical Effect Observation of Shuxuetong Injection in the Treating of Cervical Spondylosis of Vertebral Artery Type

目的观察疏血通注射液对椎动脉型颈椎病的治疗效果。方法将诊断明确的椎动脉型颈椎病患者300例随机分为治疗组和对照组,各150例,治疗组采用疏血通注射液治疗,对照组采用桂哌齐特注射液治疗,治疗前后检测两组血液流变学指标,2周后评价疗效。结果治疗组总有效率为94.0%,对照组总有效率为88.0%,两组疗效比较,差异无统计学意义(P>0.05)。治疗前两组患者高切黏度、低切黏度、血浆黏度及纤维蛋白原比较,差异无统计学(P>0.05);治疗后治疗组高切黏度、低切黏度、血浆黏度及纤维蛋白原均低于对照组,差异有统计学意义(P<0.05)。结论疏血通注射液能改善椎动脉型颈椎病的血液流变学指标,有良好的临床疗效。

Objective To observe the effect of Shuxuetong injection in the treating of cervical spondylosis of vertebral artery type.Methods 300 patients who were diagnosed with cervical spondylosis of vertebral artery type were randomly divided into 2 groups,teatment group for 150 cases,treated with Shuxuetong injection;Control group for 150 cases,treated with Cinepazide Maleate injection（CMI）.Hemorheology were detected before and after treatment,clinical effect was evaluated after 2 weeks treatment.Results The total effective rate was 94.0% in the treatment group,the total effective rate was 88.0% in the control group,compared two groups,the difference was not statistically significant（P 0.05）.Before after,two groups of patients before treatment,high shear viscosity,low shear viscosity,plasma viscosity and fibrinogen,the difference was not statistically（P 0.05）;After treatment,the treatment group high shear viscosity,low shear viscosity,plasma viscosity and fibrinogen were lower than the control group,the difference was statistically significant（P 0.05）.Conclusion Shuxuetong injection can improve the patients indexes of hematological rheology and has a good clinical effect on cervical spondylosis of vertebral artery type.