喹硫平两种给药方法治疗精神分裂症急性期患者的对照分析

目的探析喹硫平两种剂量对精神分裂症急性期患者快速加量治疗的临床效果。方法住院患者130例,随机分为两组各65例。对照组行常规剂量治疗,治疗组行加量快速治疗,比较两组患者的临床效果。结果所有患者PANSS减分率均显著提高,但同期比较,两组无显著差异;治疗组有效率和对照组无显著差异。结论喹硫平加量快速治疗精神分裂症急性期患者临床疗效与常规剂量相当,值得临床推广。

Objective To discuss the clinical effects of two kinds of rapid and added dosage therapy of quetiapine for treatment of acute stage of schizophrenia patients. Methods 130 patients were randomly divided into two groups both with 65 cases. Control group adopted routine dosage therapy and treatment group adopted rapid and added dosage therapy. Clinical effects of both groups were compared. Results PANSS score-reducing rate of all patients increased obviously. But on contemporary comparison, there was no obvious difference. No obvious difference existed between effective rates of treatment group and control group. Conclusion Rapid and added dosage therapy of quetiapine for treatment of acute stage of schizophrenia patients has an equal effect with routine dosage and is worth of being popularized in clinical work.