2003-2011年六安市流行性脑脊髓膜炎流行特征分析

Analysis on epidemiological features of the Meningococcal Disease in Lu’an City from 2003 to 2011

目的对2003-2011年六安市流行性脑脊髓膜炎(简称流脑)的流行趋势和流行特征进行分析,为预防控制工作提供参考。方法对流脑监测系统收集的监测资料和法定传染病报告信息系统报告的疫情信息进行描述性流行病学分析。结果 2003-2011年期间六安市流脑年均发病率和病死率分别为0.229/10万和5.56%。每年的12月至次年的4月为流脑高发季节。报告的总病例中74.60%的职业为学生,69.05%的病例分布在10～19岁年龄组。实验室检测共培养出C群脑膜炎奈瑟氏双球菌10株,A群2株,B群1株。传染病网络报告信息系统显示7例脑脊液标本中检出奈瑟氏菌抗原C阳性。结论 C群流脑是该市流脑流行的优势菌群,学校是防控重点场所。应采取规范疫苗接种,广泛开展健康宣教,强化疾病监测等措施做好流脑的防控工作。

Objective To understand the epidemiological characteristics of the Meningococcal disease in Lu’an City in Anhui Province from 2003 to 2011,and to provide evidence for improving the prevention and controlling work.Methods The epidemiologic data from Meningococcal disease Surveillance System and the National Diseases Reporting Information System during 2003-2011 were analyzed.Results During 2003 to 2011,126 cases of Meningococcal disease were reported,and 7 patients were dead.The annual average incidence rate was 0.229 /105,and the fatality rate was 5.56%.The incidence peak was found during December to following April.High incidence of age group of the cases were 10-19 and 74.60% cases were students.10 strains of Serogroup C were separated and C group Antigen was found in 7 cases.Conclusions Serogroup C is a prevalent strain in Lu’an City now.We should take synthetic control measures on health education,disease surveillance and immunization vaccine,specially in the schools.