Q开关紫翠宝石激光治疗Peutz-Jeghers综合征色素沉着的疗效分析

Clinical analysis of the effect of Q-switched alexandrite laser on the treatment of pigmentagion of Peutz-Jeghers syndrome

目的:观察Q开关紫翠宝石激光治疗Peutz-Jeghers综合征色素沉着的临床疗效及不良反应。方法:采用Q开关紫翠宝石激光对18例Peutz-Jeghers综合征患者的色素沉着进行治疗,治疗次数1～3次,每次治疗间隔3～6个月,根据治疗前后的照片对比判定疗效。结果:18例患者,11例痊愈(占61.1%),6例显效(占33.3%),1例有效(占5.6%),总有效率达94.4%,无瘢痕等严重不良反应。结论:Q开关紫翠宝石激光治疗Peutz-Jeghers综合征临床疗效佳,不良反应少。

Objective To observe the clinical effect and adverse reactions of Q-switched alexandrite laser on the pigmentation of Peutz-Jeghers syndrome （PJS）. Methods Q-switched alexandrite laser were adopted for treating pigmentation of PJS in 18 cases at 1 N3 times with an interval of 3 ～6 months. The clinical effects were judged according to comparison between photographs taken before and after treatment. Results 11 cases were cured （61.6%）, 6 cases showed marked improvement （33.3%）, 1 cases showed eftective improvement （5.6%）. The total effective rate was 94.4%. No scar and other severe adverse reactions were observed. Conclusions Q-switched alexandrite laser can be used with good clinical effect and few complications on the treatment of pigmentation of PJS.