逆行撕除法联合MMC及自体角膜缘干细胞移植治疗翼状胬肉

Retrograde rip of pterygium combined with MMC and limbal stem cell autograft transplantation

目的:观察逆行撕除法联合丝裂霉素C(MMC)及自体角膜缘干细胞移植治疗翼状胬肉的临床疗效。方法:对89例89眼行逆行撕除法治疗翼状胬肉,同时使用MMC局部浸敷及自体角膜缘干细胞移植,观察手术后角膜创面修复时间及术后复发率。术后随访1～12(平均5)mo。结果:所有患者的角膜创面在术后3～7(平均5)d恢复,移植片生长良好,5例复发,复发率为6%。结论:逆行撕除法联合MMC及自体角膜缘干细胞移植可有效治疗翼状胬肉,降低术后复发率。

AIM： To observe the therapeutic effects on the retrograde rip of pterygium combined with mitomycin C （MMC） and limbal stem cell autograft transplantation in the treatment of pterygium. METHODS： Pterygium in 89 eyes of 89 cases was ripped retrogradely by tweezers combined with MMC and limbal stem cell autograft transplantation. Postoperatively epithelial healing time of corneal wound and the recurrent rate were observed. All patients were followed up for 1 month-12 months. RESULTS： The epithelial cure time of corneal wound was 3-7 days in all cases. The grafts survived very well. Five cases recurred and the recurrent rate was 6%. CONCLUSION： Retrograde rip of pterygium combined with MMC and limbal stem cell autograft transplantation is an effective method and decreases the recurrent rate.