腹腔镜下子宫动脉阻断术治疗子宫肌瘤的研究进展

Laparoscopic Uterine Artery Occlusion for Treatment of Symptomatic Uterine Fibroids

近年来,随着妇科微创技术的不断发展,腹腔镜下子宫动脉阻断术逐渐被应用于治疗子宫肌瘤。国内外文献报道,用该术式治疗子宫肌瘤可达到满意的临床疗效,术后能明显缓解月经异常症状,缩小子宫体积,有效降低子宫肌瘤的复发率。另外,该技术治疗子宫肌瘤的机制尚不完全明确,目前认为可能与子宫的血供特点、子宫肌瘤与平滑肌组织的凝血-纤溶激活系统差异有关。现对近年来该技术的临床应用情况以及相关机制研究进行综述。

In recent years,with the development of gynecologic laparoscopy technology,uterine artery occlusion by laparotomy（UAOL） was performed as a primary treatment for symptomatic uterine fibroids.According to the documents reported,UAOL for treatment of uterine fibroids showed favorable clinic outcomes,including of relieving menometrorrhagia,decrease of uterine volume and decline of recurrence rate of fibroids.However,the therapeutic mechanism of UAOL remains unclear.It was thought that the mechanism of UAOL was mostly related to uterine blood supply and uterine intramural arterial paths and the difference in coagulation-fibrinolysis system between uterine myometrium and fibroids.So,the study reviewed and generalized many documents about clinic effects and therapeutic mechanism of UAOL.