介入性宫内干预后绒毛膜羊膜分离的临床分析

Chorioamniotic Membrane Separation after Invasive Intrauterine Intervene

目的:探讨介入性宫内干预后出现绒毛膜羊膜分离的临床特点及高危因素。方法:回顾性分析中山大学附属第一医院胎儿中心2001年7月—2010年6月行介入性宫内干预术后超声检查发现绒毛膜羊膜分离的病例,介入性干预包括羊水减量术213例、宫内输血28例、电凝脐带术28例。结果:269例宫内干预术后的病例中,共发现9例绒毛膜羊膜分离,羊水减量术后4例(4/213,1.88%),宫内输血术后1例(1/28,3.6%),电凝脐带术后4例(4/28,14.3%)。结论:电凝脐带术后绒毛膜羊膜分离发生率高,双胎输血综合征及羊水过多可能是绒毛膜羊膜分离发生的高危因素。

Objective：To investigate the clinical characteristics of the chorioamniotic membrane separation（CMS） after invasive intrauterine treatment.Methods：Retrospective review of a maternal population undergoing intra uterine therapy at a single center following the postoperative ultrasound to follow-up for membrane separation.The intrauterine procedures consisted of cord coagulation reduction,amnioreduction,intrauterine transfusion in Center of Fetal,the First Affiliated Hospital of Sun Yatsen University from 2001 July to 2010 June.Results：From 2001 to 2010,we found 9 cases of CMS in 269 cases after invasive procedure.4 cases（4/213,1.88%） had amnioreduction,1 case（1/28,3.6%） had intrauterine transfusion and 4 cases（4/ 28,14.3%）had cord coagulation reduction.Conclusions：There was a higher risk of CMS after fetoscopic cord coagulation reduction.