摘要
目的:研究鼠妇水提物(water abstracts of Armadillidium vulgare,AVW)对凝血系统的影响。方法:观察AVW连续灌胃对小鼠凝血时间、出血时间及家兔凝血酶原时间、优球蛋白溶解时间的影响。结果:AVW灌胃可延长小鼠凝血时间与出血时间,同时还能缩短家兔优球蛋白溶解时间(eugloblin lysis time,ELT)。结论:AVW具有较好的抗凝血及促纤溶作用,提示其中含有具有此类药理活性的有效成分。
Objective: To investigate the effects of AVW (water abstracts of Armadillidium vulgate ) on coagulation system. Methods: To study the pharmacological effects of AVW by coagulation time (CT), bleeding time (BT) in mice and Pro- thrombin time (PT), euglobulin lysis time (ELT) in rabbits. Results: The results showed that po AVW significantly prolonged CT and BT in mice, shortened ELT in rabbits. Conclusions: It is suggested that the decrease of ELT and increase of CT might be contributed to the potent thrombolytic effect of AVW.
出处
《宜春学院学报》
2013年第6期79-80,共2页
Journal of Yichun University
基金
2012年江西省宜春市科技计划指导性项目"鼠妇水提物对凝血功能影响的实验研究"(JXYC2012KSB0002)