小儿室间隔缺损围手术期中两种抗菌药的应用对比分析

Comparative Analysis on Application of Two Antibacterials during Entire Perioperative Period of Pediatric Ventricular Septal Defect

目的:比较两种抗菌药在本院小儿室间隔缺损围手术期中应用的疗效及经济学差异。方法:回顾性分析2011年本院行室间隔缺损手术病历351份,按预防性使用抗菌药品种分为头孢呋辛组(176例)和头孢美唑组(175),统计两组的相关数据并进行比较分析。结果:两组患者的抗菌药日均费用、抗菌药总费用指标差异有统计学意义(P<0.05);头孢呋辛组较头孢美唑组抗菌药日均费用和抗菌药总费用分别节省约42元和271元。两组患者术后感染率差异无统计学意义。结论:头孢呋辛较头孢美唑在经济学方面有优势,可以有效降低医疗费用。

Objective：To compare the curative effect and economic difference between two kinds of anlibacterials applied during the entire perioperative period of pediatric ventricular septal defect in our hospital.Method;By the retrospective survey,351 medical records of pediatric ventricular septal defect in our hospital in 2011 were analyzed.Based on the application of cefuroxime（176 eases） or cefmetazole（175 cases）,the data were divided into two groups and compared the effect and economic difference.Result：There was significant difference in daily cost and total cost between the two groups（P ＆lt;0.05）.The daily cost and total cost in the group with cefuroxime was respectively 42 yuan and 271 yuan less than that in the group with cefmetazole.There is no statistically significant difference in postoperative infection between the two groups.Conclusion：Cefuroxime has an advantage in economics with lower cost than cefmetazole,which can lighten the economic burden of the patients.