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昔萘酸沙美特罗吸入给药剂型的研究进展 被引量：1

Advances in research on inhaled drug delivery system of salmeterol xinafoate
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摘要 昔萘酸沙美特罗主要用于治疗长期哮喘、慢性支气管炎和慢性阻塞性肺病,其常用给药途径是吸入给药。本文结合吸入给药常用剂型,如吸入气雾剂、干粉吸入剂、脂质体和微粒的特点,对昔萘酸沙美特罗吸入给药剂型的设计与研究情况做一综述。 Salmeterol xinafoate is mainly used in the treatment of persistent asthma,chronic bronchitis and chronic obstructive pulmonary diseases.This paper made a comprehensive review of the design and research on the inhaled salmeterol xinafoate delivery system,in combination with the features of those commonly used inhaled drug dosage forms,such as inhaled aerosol,dry powder inhaler,drug-loaded liposome and microparticles.
作者 李慧 王众勤 杜丽 李凤前
机构地区 上海市第八人民医院药剂科 湖北医药学院药学系
出处 《药学服务与研究》 CAS CSCD 2013年第3期216-219,共4页 Pharmaceutical Care and Research
基金 国家自然科学基金资助项目(30973661)
关键词 昔萘酸沙美特罗 投药 吸入 综述 salmeterol xinafoate administration inhalation review
分类号 R974.3 [医药卫生—药品]
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参考文献23

  • 1Handoko A.Ian I.,Peter S J. Influence of "the polydispersity of 1he added fine lactose on lhe dispersion of salmeterol xin- afoate from mixtures for inhalaticm[J]. Eur J Pharm Sci, 2009,36(2 3),265 -274.
  • 2汤玥,朱家壁,陈西敬.新型肺部给药系统——吸入粉雾剂[J].药学学报,2009,44(6):571-574. 被引量：14
  • 3杜小莉,朱珠,傅强,李大魁,许文兵.沙丁胺醇气雾剂在健康受试者体内的药代动力学及生物利用度研究[J].药学学报,2001,36(8):616-620. 被引量：11
  • 4Mansori F,Nemat Khorasani A, Boskabady M H,et al. The effect of inhaled salmeterol, alone and in combination with fluticasone propionate,on management of COPD patients[J]. Clin Respir J,2010,4(4) :241-217.
  • 5Kempsford R, Handel M, Me|'tta R,et aL. Comparison of the systemic pharmacodynamic effects and pharmacokinetics of salmeterol delivered by CFC propellant and non-CFC propel lant metered dose inhalers in healthy subjects[J]. Respir Med,2005,99(Suppl A) :S11-S19.
  • 6Chopra N,Williams M, Rimmer M,et al. Salmeterol HFA is as effective as sahneterol GFC in children and aduhs with per sistent asthma[J]. Respir Med,2005,99(Suppl A) :S1-S10.
  • 7Ferguson C- T, Funck Brentano C, Fischer T, etal. Cardiovas cular safety of salmeterol in COPD[J]. Chest, 20(/3,123 (6) : 1817- 1824.
  • 8Perera B J. Salmetero multiccnter asthma research trial (SMART) : interim analysis shows increased risk of asthma related deaths[J]. Ceylon Med j ,2003,48(3) :99.
  • 9李凤前,胡晋红,朱全刚.干粉末吸人给药系统[J].围外医学药学分册,200l,28(3):167-170.
  • 10Sumby B,Slater A, Atkins P J, et al. Review of dry powder inhalers[J]. Adv Drug Deliv Rev,1997,26(1):51- 58.

二级参考文献25

  • 1[1]Evans ME, Paterson JW, Richards AJ, et al. Pharmacokinetics of inhaled salbutamol in asthmatic patients [J]. Br J Pharmacol, 1971,43(2):466-467.
  • 2[2]Walker SR, Evans ME, Richards AJ, et al. The clinical pharmacology of oral and inhaled salbutamol [J]. Clin Pharmacol Ther, 1972,13(6):861-867.
  • 3[3]Newnham DM, McDevitt DG, Lipworth BJ. Comparison of the extrapulmonary β2-adrenoceptor responses and pharmacokinetics of salbutamol given by standard metered dose inhalers and modified actuator device [J]. Br J Clin Pharmacol, 1993,36(5):445-450.
  • 4[4]Gupta RN, Fuller HD, Dolovich MB. Optimization of a column liquid chromatographic procedure for the determination of plasma salbutamol concentration [J]. J Chromatogr B, 1994,654(2):205-211.
  • 5[5]Emm T, Lesko LJ, Leslie J. Determination of albuterol in human serum by reversed-phase high-performance liquid chromatography with electrochemical detection [J]. J Chromatogr, 1988,427(1):188-194.
  • 6[6]Wong BJO, Hargeave FE. Bioequivalence of metered-dose inhaled medications [J]. J Allergy Clin Immunol, 1993,92(3):373-379.
  • 7[7]Chrystyn H. Standards for bioequivalence of inhaled products [J]. Clin Pharmacokinet, 1994,26(1):1-6.
  • 8[8]Lipworth BJ. Pharmacokinetics of inhaled drugs [J]. Br J Clin Pharmacol, 1996,42(6):697-705.
  • 9[9]Morgan DJ, Paull JD, Richmond BH. Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate [J]. Br J Clin Pharmacol, 1986,22(5):587-593.
  • 10[10]Clark DJ, Smith JG, Clark G, et al. Lung bioavailability of generic and innovator formulations of inhaled salbutamol [J]. Eur Respir J, 1995,8(Suppl 19):259s-259s.

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药学服务与研究
2013年 第3期

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