期刊文献+

艾普拉唑联合莫沙必利治疗胃食管反流病的临床研究 被引量:4

下载PDF
导出
摘要 选取64例胃食管反流病患者分为奥美拉唑组和艾普拉唑组,两组服用相应药物后同时服用莫沙必利5mg进行治疗。结果艾普拉唑组总有效率(93.8%)显著高于奥美拉唑组总有效率(75.0%),且两组差异对比具有统计学意义(P<0.05);血常规及血生化检查显示艾普拉唑组l例患者的谷丙转氨酶有所升高,奥美拉唑组2例患者的白细胞有所减少,经相应措施改善后病情恢复正常。艾普拉唑联合莫沙必利对胃食管反流病进行治疗,可促使胃酸分泌的降低,减少胃酸反流,使食管黏膜得以有效修复,从而缓解胃食管反流症状,具有安全可靠的治疗效果。
作者 秦兰静
出处 《现代诊断与治疗》 CAS 2013年第5期1132-1133,共2页 Modern Diagnosis and Treatment
  • 相关文献

参考文献2

二级参考文献8

  • 1CASTRO D, MORENO M A, TORRADO S, et al. Comparison of derivative spectrophotometric and liquid chromatograpic methods for the determination of omeprazole in aqueous solutions during stability studies [ J ]. J Pharm Biomed Anal, 1999,21 (2) : 291-298.
  • 2KITA T, TANIGAWARA Y, AOYAMA N, et al. CYP2C19 CYP2C19 genotype related effect of omeprazole on intragastric pH and antimicrobial stability [ J ]. Pharm Res, 2001,18 ( 5 ) : 615- 621.
  • 3EKPE A, JACOBSEN T. Effect of various salts on the stability of lansoprazole, omeprazole, and pantoprazole as determined by high-performance liquid chromatography [ J ] . Drug Dev Ind Pharm, 1999,25 (9) : 1057-1065.
  • 4Kwon D, Chae JB, Park CW, et al.Effects of IY - 81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo [ J ]. Arzneimittelforschung, 2001,51 (3) :204.
  • 5Kim E J, Lee RK, Lee SM, et al. General pharmacology of IY - 81149, a new proton pump inhibitor [ J ]. Arzneimittelforschung , 2001,51 ( 1 ) : 51.
  • 6Kil BJ, Kim IW, Shin CY, et al. Comparison of IY81149 with omeprazole in rat reflux oesophagitis [ J ], Auton Pharmacol, 2000,20(5 - 6) :291.
  • 7Periclou AP, Goldwater R, Lee SM, et al. A comparative pharmacodynamic study of IY- 81149 versus omeprazole in patients with gastroesophageal reflux disease [ J ]. Clin Pharmacol Ther, 2000,68 (3) : 304.
  • 8Ho KY, Kuan A, Zano F, et al. Randomized, parallel, double - blind comparison of the ulcer- healing effects of ilaprazole and omeprazole in the treatment of gastric and duodenal ulcers[J] . J Gastroenterol, 2009,44(7) :697.

共引文献40

同被引文献24

引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部