microRNA与胎盘的相关研究进展
摘要
microRNA(miRNAs)存在于各种生物体中,在调控基因表达方面发挥着重要的生物学作用,主要参与细胞增殖、凋亡、细胞分化、发育和逆境应答等多种生理及病理过程。胎盘作为母-胎之间的一个交换器官,对胎儿的生长发育有重要作用。miRNAs在胎盘中广泛及特异性表达,维持胎盘功能,以便适应胎盘发生的各种病理变化,从而维持胚胎的正常发育。在此就胎盘中miRNAs表达及最新研究进展做一简短综述。
出处
《南昌大学学报（医学版）》
CAS
2013年第3期76-78,共3页
Journal of Nanchang University：Medical Sciences
参考文献20
-
1Landgraf P,Rusu M, Sheridan R, et al. A mammalian microR NA expression atlas based on small RNA library sequencing [J]. Cell,2007,129(7) :1401- 1414.
-
2Tsai K W,Kao H W,Chen H C,et al. Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells[J]. Epigenetics,2009,4(8) :587-592. Noguer Dance M, Abu Amero S, A1 Khtib M,et al. The pri- matespecific microRNA gene cluster (C19MC) is im.
-
3printed in the placenta[J]. Hum Mol Genet, 2010,19 : 3566- 3582.
-
4Ren J, Jin P, Wang E, et al. MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells [J]. J Transl Med,2009,23(7) :20.
-
5Barad O, Meiri E, Avniel A, et al. MicroRNA expression detec- ted by oligonucleotide microarrays: system establishment and expression profiling in human tissues[J]. Genome Res, 2004, 14(12) :2486 -2494.
-
6Pineles B L, Romero R, Montenegro D, et al. Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia[J]. Am J Obstet Gynecol, 2007, 196(3) :261.e1- e6.
-
7Heazell A E,Brown M,Worton S A,et al. Review:The effects of oxygen on normal and pre-eclamptic placental tissue insights from metabolomics[J]. Placenta,2011,32(S 2) :S119 -S124.
-
8Fasanaro P,D' Alessandra Y, Di Stefano V, et al. MicroRNA- 210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3 [J]. J Biol Chem,2008,283(23) :15878 -15883.
-
9Dunwoodie S L. The role of hypoxia in development of the Mammalian embryo[J]. Dev Ce11,2009,17(6) :755-773.
-
10Mo F E,Muntean A G,Chen C C,et al. CYR61 (CCN1) is es sential for placental development and vascular integrity[J]. Mol Cell Biol,2002 ,22(24):8709- 8720.
-
1李涵,顾蔚蓉.micro RNA与子痫前期的研究进展[J].实用妇产科杂志,2014,30(12):896-899. 被引量：2
-
2刘冰.生物信息学在脑疾病研究中的应用[J].科研信息化技术与应用,2009(3):62-69.
-
3傅斌生（综述）,陈规划（审校）.肝细胞癌蛋白质组学研究进展[J].国际肿瘤学杂志,2007,34(6):466-469.
-
4王文灏,曹银芳,李慧君.循环微小RNA在临床疾病诊治中的研究进展[J].内蒙古医学杂志,2016,48(1):62-64. 被引量：1
-
5魏鹏,高飞,陈鑫磊,张志宏,胡召元,刘以训.VEGF及其受体在早期胎盘发生过程中的表达[J].Developmental and Reproductive Biology,2001,10(B10):72-72.
-
6高飞,傅国强,丁峰,刘以训.胎盘发生过程中的细胞凋亡[J].生理学报,2001,53(6):409-413. 被引量：6
-
7陈敦金,陈兢思.早产预测[J].中华产科急救电子杂志,2014,3(1):33-37. 被引量：5
-
8王冠楠,李冬杰,陈玮娜,张萃,杨文志,李世杰.DLK1-DIO3印记区域的miRNAs与疾病的发生[J].生物化学与生物物理进展,2017,44(4):316-325.
-
9陈静廷,马露,杨晋辉,张娟霞,李发第,卜登攀.差异蛋白质组学在乳蛋白研究中的应用进展[J].动物营养学报,2013,25(8):1683-1688. 被引量：14
-
10高文龙,吉蕾,李玉侠,王雁玲.胎盘发生中的表观遗传学[J].医学分子生物学杂志,2010,7(1):59-65. 被引量：2
