摘要
目的对圆瓣姜花(Hedychium forrestii Diels.)的根茎部分进行化学成分研究。方法对圆瓣姜花根茎的95%乙醇提取物经乙酸乙酯萃取。乙酸乙酯萃取物经硅胶、十八烷基硅烷键合相(ODS)、葡聚糖醚凝胶SephadexLH-20等色谱方法进行分离纯化,并运用MS、NMR等波谱方法鉴定化合物的结构。结果从圆瓣姜花中分离鉴定了5个化合物,分别为:5-hydroxy-3,7,4′-trimethoxyflavone(I),3,5-dihydroxy-7,4′-dimethoxyflavone(II),5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxy-phenyl)-3-heptanone(III),(5R)-5-hydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-3-heptanone(IV),stigmast-4-en-3-one(V)。结论 5个化合物均为从该植物中首次分离得到。
Objective To research the chemical constitutes isolated from the rhizomes of Hedychium forrestii Diels. Methods The rhizomes of H. forrestii Diels. were extracted with 95% ethanol,which was suspended in water and then extracted with ethyl acetate. The ethyl acetate extract was extensively separated over chromatographic methods,including silica gel,octadecylsilane (ODS),and Sephadex LH-20. These compounds were elucidated by extensive spectroscopic analysis (MS, NMR,etc. ). Results five compounds,[5-hydroxy-3,7,4'-trimethoxyflavone (Ⅰ),3,5-dihydroxy-7,4'-dimethoxyflavone (Ⅱ),5-hydroxy-7-(4-hydroxy-3- methoxyphenyl)-1-(4-hydroxy-phenyl)-3-heptanone (Ⅲ), (SR)-5-hydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxy-3- methoxyphenyl)-3-heptanone (Ⅳ),stigmast-4-en-3-one (Ⅴ). ] were isolated and identified. Conclusion Five compounds were all isolated from Hedychium forrestii for the first time.
出处
《云南中医学院学报》
2013年第3期28-30,共3页
Journal of Yunnan University of Traditional Chinese Medicine
基金
国家自然科学基金(NO:81060262)
云南省中青年学术技术带头人后备人才项目(NO:2010CI047)
关键词
姜科
圆瓣姜花
化学成分
Zingiberaceae
hedychium forrestii diels.
chemical constituents