钙调神经磷酸酶信号通路在骨骼肌运动适应作用中的研究进展

Research Progress of Calcineurin’s Role in Skeletal Muscle Adaptation of Training

系统的运动训练能促使运动骨骼肌的形态结构产生一系列的变化。例如骨骼肌体积增大、增粗,肌纤维类型的转变等。导致这一系列变化的内源性机制有很多,钙调神经磷酸酶信号机制就是其中一种。目前对钙调神经磷酸酶信号调节机制的研究已经得到了广大学者的认可。进一步探讨钙调神经磷酸酶在运动骨骼肌适应变化中的作用,对于深刻了解钙调神经磷酸酶信号机制有重要意义。

Studies have proved that skeletal muscle could have adaptive changes induced by training,which include conversions among the types of skeletal muscle fibers.,skeletal muscle volume increased.There’s a lot of endogenous mechanisms leading to this series of changes,the calcineurin signal mechanism is one of them.The calcineurin phosphatase signal adjustment mechanism has been recognized by the majority of scholars.It is important for a deep understanding of the calcineurin phosphatase signaling mechanisms,to further explore the role of calcineurin phosphatase in skeletal muscle fiber type transformation.