急性脑梗死合并高血压病患者左室重量指数与颈动脉内膜中层厚度的相关性研究

Correlation between left ventricular mass index and carotid intima-media thickness in acute cerebral infarction patients with hypertension

目的探讨急性脑梗死合并高血压病患者左室重量指数(LVMI)与颈动脉内膜中层厚度(IMT)之间的相关性。方法选取2008年1月至2012年1月在我院神经内科住院治疗的合并高血压病的急性脑梗死患者162例,依据血压水平分为1级、2级、3级高血压3组。用心脏彩超测量舒张末期室间隔厚度(IVST)、舒张末期左室后壁厚度(LVPWT)、左室腔舒张末期内径(LVDd),并根据患者身高和体重计算出左室重量指数(LVMI),用颈动脉彩超测量颈动脉内膜中层厚度(IMT)和颈动脉斑块。结果随着LVMI增加颈动脉内膜中层厚度亦增加;血压分级越高,IMT越大,颈动脉斑块检出率越高。结论急性脑梗死合并高血压病患者LVMI与IMT呈正相关性。

Objective To evaluate the correlation between left ventricular mass index （LVMI） and carotid intima-media thickness （IMT） in cerebral infarction patients with hypertension. Methods One hundred sixty two acute cerebral infarction patients with hypertension in our hospital from Jan. 2008 to Jan. 2012 were involved in the study. According to the hypertension diagnostic stand- ard, the patients were divided into Grades 1,2 and 3 groups. Interventricular septum thickness at end-diastole （ IVST）, posterior left ventricular wall thickness at end-diastole （LVPWT）, and the left ventricular diastolic diameter （LVDd） were measured with a Doppler echocardiography. The left ventricular mass index was calculated according to body height and weight. Carotid intima-media thickness and carotid atherosclerosis （CAS） plaque were also measured with the Doppler echocardiography. Results The LVMI was positively correlated with the carotid IMT. The blood pressure was also correlated with the carotid IMT and the plaque detection rate. Conclusions Increased LVMI and IMT were significantly associated with increased cerebral infarction with hypertension.