功率、时间和间距对离体猪心双极射频消融的影响

Effect of power, time and space on isolated pig heart bipolar radiofrequency ablation

目的研究临床条件下多参数双极射频消融在离体猪心上形成的消融灶的形态大小，评价双极射频消融的有效性和安全性。方法在预设功率（30w和40w）和灌注条件（1250mL／h）下用4mm的大头双极消融电极对新鲜离体猪心进行消融，电极间距离从12—17mm，时间从20～90S，测定交汇消融灶的长度、深度、连接率和爆破率。结果时间增加时，长度、深度、连接率、爆破率都增加；间距增加时，长度增加，深度、连接率、爆破率下降；功率增加时，长度、连接率、爆破率增加，深度减小。12mm、20s,30W，有盐水灌注（1250ml／h）时双击消融有效性和安全性最好，长度均值为19．89mm，深度均值为3．94mm，连接率100％，爆破率6％。结论双极消融可以在电极间距离12ITIE、20s、30W、有灌流（1250ml／h）时形成稳定的交汇消融灶。

Objective To investigate the effectiveness and safety of clinical bipolar radiofrequency ablation in vitro pigs hearts on different conditions. Methods The effects of bipolar radiofrequency ablation in the power of 30 W and 40 W,with a 4 mm bipolar electrode, electrode distance from 12 mm to 17 ram,time from 20 s to 90 s, cold saline perfusion（ 1250 ml/h）on isolated fresh pigs hearts were evaluated.The lesion size including lengthand depth, connection rate and blasting rate were measured. Results As time increases, the lesion length was increased, depth, connection rate, blasting rate increased;as distance increases, the lesion length was increased, connection rate ,blasting rate were reduced; as power increases, the lesion length, con- nection rate, blasting rate were increased while the depth was reduced.The effectiveness and safety was the best when using 12 ram,20 s,30 W, 1250 ml/h,the mean lesion length was 19. 89 ram, the average depth was 3.94 ram,connection rate was 100%, blasting rate was 6%.Conclusion Bipolar radiofrequency ablation in power of 30 W, bipolar electrode with 12 mm,20 s, 1250 ml/h waseffectiveness and safety.