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加巴喷丁和羟嗪用于阴式子宫全切术的临床观察

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摘要 目的观察加巴喷丁和羟嗪对阴式子宫全切术患者术前焦虑和术后疼痛的影响。方法将90例择期行阴式子宫全切术患者随机分为A组、B组和C组各30例。A组术前予加巴喷丁;B组术前予羟嗪;C组术前予安慰剂。采用状态—特质焦虑量表(STAI)对患者给药前,给药后2h及麻醉诱导前的焦虑水平进行评估;手术前和术后2、6、12、24、48h进行疼痛评分(VAS),同时调查患者对术前抗焦虑用药的满意度。结果给药后2h及麻醉诱导前A组和B组STAI评分均低于C组,差异均有统计学意义(P<0.05)。术后2、6、12、24、48hA组和B组VAS评分均低于C组,差异均有统计学意义(P<0.05)。A组和B组患者满意度均高于C组,且差异均有统计学意义(P<0.05)。结论加巴喷丁和羟嗪能均能明显减轻阴式子宫全切术患者的术前焦虑和术后疼痛,并能提高患者对术前抗焦虑用药的满意度,且不增加不良反应的发生率。
作者 王小平
出处 《临床合理用药杂志》 2013年第19期75-76,共2页 Chinese Journal of Clinical Rational Drug Use
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