宫颈癌前哨淋巴结微转移的研究与应用现状

The research progress and using of sentinel lymph node micrometastasis in cervical cancer

宫颈癌是严重威胁女性健康的恶性肿瘤之一。其主要转移途径为淋巴结转移。前哨淋巴结是肿瘤发生淋巴结转移的第一站，由于传统组织病理学检查具有一定的局限性，使某些存在于前哨淋巴结的微转移或孤立肿瘤细胞被忽略，使其发展成为临床转移。怎样把前哨淋巴结示踪与微转移检测技术两者结合，是近年来研究的热点，其具有重要的临床意义，可以使得某些宫颈癌患者避免不必要的盆腔淋巴结清扫术，从而降低手术并发症。本文就近年来对宫颈癌前哨淋巴结微转移的研究及临床应用现状做一综述。

Cervical cancer is one of the malignant tumors which serious threat to women＇s health. The main route of cervical cancer metastasis is lymphatic metastasis. The sentinel lymph node is the first station of lymphatic metastasis. Because of the limitations of traditional histopathological examination, some micrometastasis exists in sentinel lymph node, or isolated tumor cells are ignored which develops clinical metastasis. How to combine sentinel lymph node tracking with micrometastasis detection is the hotspot recently. The clinical significance is important,because it can make some cervical cancer patients avoiding unnecessary pelvic lymph node dissection, accordingly reducing operation complications. This article reviewed the research progress and using of sentinel lymph node micrometastasis in cervical cancer.