合子草的化学成分与药理活性研究进展

Advances in studies on chemical constituents and pharmacological activities of Actinostemma lobatum Maxim.

目的对合子草的研究进展进行综述。方法查阅了关于合子草研究的中外文献资料,依据其中的25篇文献从化学成分、药理活性方面对其进行比较全面地综述。结果与结论合子草(Acti-nostemma lobatum Maxim.)为葫芦科盒子草属植物,含有大环内酯三萜皂苷和人参属植物具有的达玛烷型三萜类化合物,发现的这些皂苷类物质具有显著的抗肿瘤活性,具有一定的开发研究前景。

Objective To review the research progress of Actinostemma lobatum Maxim.Methods Referring to domestic and foreign literatures,the chemical compositions,and pharmacological activities of Actinostemma lobatum Maxim.were reviewed.Results and Conclusions Actinostemma lobatum Maxim.,a herb of Cucurbitaceae family,contains cyclic bisdesmosides and dammarane-type triterpenoids,which have significant antitumor activity,have a perspective of research and development.