90例膀胱移行细胞癌的病理观察及其预后探讨

Pathological Observation on 90 Cases of Bladder Transitional Cell Carcinoma and Its Prognosis

本文报告光镜观察90例膀胱移行细胞癌,其中12例进行了超微结构观察。本组男性71例,女性19例,男女之比为3.5:1。年龄32岁～79岁。对于移行细胞癌的组织形态及超微结构特征,作了较详细的描述。根据随访结果表明,肿瘤体积大,分化程度低,浸润深度越深及血管或淋巴管内癌组织浸润者预后差。对超微结构作了简要的讨论。

Ninety specimens of pathologically confirmed transitional cell carcinoma of the urinary bladder were studied. The patients consisted of 71 male and 19 female with a male/femai ratio of 3.5:1. Their age was ranged from 32 to 79. 12 specimens were studied with electron microscope. The histopathological and ultrastructural features of transitional cell carcinoma were described. Our fol-lowup data of the cases revealed that the larger a tumor,the lower its differentiation, the deeper its invasion, and the more extensive the involvement of lymphatic and blood vessels, the poorer the prognosis of the tumor. In addition the ultrastructural characteristics of transitional oell carcinoma were briefly discussed.