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对硝基苯基-α-D-吡喃木糖苷的合成

Synthesis of p-nitrophenyl α-D-xylopyranoside
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摘要 以D-木糖为原料,经全乙酰化、Helferich糖苷化、脱保护基3步反应,合成标题化合物。对Helferich糖苷化条件的催化剂进行了研究,结果表明:在SnCl4的催化下,α-立体选择性最好,产率最高。 p-Nitrophenyl a-D-xylopyranoside was synthesized with D-xylose as a raw material by acetylation,Helferich glycosidation and deacetylation. The effect of catalyst on the Helferich glycosidation was studied. The results indicated that SnCI4 was the best catalyst for the a-stereoselectivity and high yield.
作者 曾森 陈朗秋 刘灯峰 李宏伟 伍桂龙 廖媛薇
机构地区 湘潭大学化学学院环境友好化学与应用省部共建教育部重点实验室
出处 《化学试剂》 CAS CSCD 北大核心 2013年第7期599-600,652,共3页 Chemical Reagents
基金 湖南省自然科学基金资助项目(10JJ6023 05JJ40054) 湘潭大学第八批大学生创新基金研究项目(30) 博士科研启动费(05QDZ09)
关键词 立体选择性合成 Helferich糖苷化 对硝基苯基-α-D-吡喃木糖苷 SNCL4 stereoselective synthesis Helferich glycosidation p-nitrophenyl a-D-xylopyranoside SnC14
分类号 O629.13 [理学—有机化学]
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参考文献11

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二级参考文献12

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化学试剂
2013年 第7期

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