期刊文献+

右美托咪啶对老年腹部手术患者全麻恢复期质量的影响 被引量:3

下载PDF
导出
摘要 老年外科手术患者常合并各种心血管疾病,在全麻恢复期气管导管拔除和手术创伤等伤害性刺激造成的疼痛町诱发严重应激反应,导致血压急剧升高、心肌耗氧量增加,极易诱发心血管事件。右美托咪啶是一种新型a2肾上腺素能受体激动剂,具有镇痛、镇静、抗交感神经兴奋作用,且无明显呼吸抑制,可娃著减少阿片类药物及吸人性麻醉药的用量,因而已被广泛应用于临床镇静和辅助临床麻醉。本研究拟评价右美托咪啶对老年腹部手术患者全麻恢复期质量的影响,为临床应川提供参考。
出处 《浙江医学》 CAS 2013年第11期1079-1081,共3页 Zhejiang Medical Journal
  • 相关文献

参考文献7

  • 1Subramaniam B, Panzica P J, Novack V, et al. Continuous periop- erative insulin infusion decreases major cardiovascular events in patients undergoing vascular surgery: a prospective, randomized trial[J]. Anesthesiology, 2009, 110(5): 970-977.
  • 2Gupta P, Whiteside W, Sabati A, et al. Safety and efficacy of pro- longed dexmedetomidine use in critically ill children with heart disease[J]. Pediatr Crit Care Med, 2012, 13(6): 660-666.
  • 3Chrysostomou C, Schmitt C G. Dexmedetomidine: sedation, anal- gesia and beyond[J]. Expert Opin Drug Metab Toxicol, 2008, 4(5): 619-627.
  • 4Dahmani S, Rouelle D, Gressens P, et al. Characterization of the postconditioning effect of dexmedetomidine in mouse organotyp- ic hippocampal slice cultures exposed to oxygen and glucose deprivation[J]. Anesthesiology, 2010, 112(2): 373-383.
  • 5Bicer C, Esmaoglu A, Akin A, et al. Dexmedetomidine and me-peridine prevent postanaesthetic shivering[J]. Eur J Anaesthesiol, 2006, 23(2): 149-153.
  • 6胡宪文,张野,孔令锁,翁立军,蒋玲玲,李云.不同剂量右美托咪啶抑制气管插管诱发患者心血管反应效应的比较[J].中华麻醉学杂志,2010,30(11):1304-1306. 被引量:178
  • 7Halt J E, Uhrich T D, Barney J A, et al. Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions [J]. Anesth Analg, 2000, 90(3): 699-705.

二级参考文献7

  • 1Kanaidel M,Fukusakil M,Tamural S,et al.Hemodynamic and catecholamine responses during tracheal intubation using a lightwand device (Trachlight) in elderly patients with hypertension.J Anesth,2003,17(3):161-165.
  • 2Yoo KY,Jeong SW,Kim SJ,et al.Cardiovascular responses to endotracheal intubation in patients with acute and chronic spinal cord injuries.Anesth Analg,2003,97(4):1162-1167.
  • 3Kunisawa T,Nagata O,Nagashima M,et al.Dexmedetomidine suppresses the decrease in blood pressure during anesthetic induction and blunts the cardiovascular response to tracheal intubation,J Clin Anesth,2009,21(3):194-199.
  • 4Adachi YU,Takamatsu I,Watanabe K,et al.Evaluation of the cardiovascular responses to fiberoptic orotracheal intubation with television monitoring:comparison with conventional direct laryngoscopy.J Clin Anesth,2000,12(7):503-508.
  • 5Chrysostomou C,Schmitt CG.Dexmedetomidine:sedation,analgesia and beyond.Expert Opin Drug Metab Toxicol,2008,4(5):619-627.
  • 6Bekker AY,Basile J,Gold M,et al.Dexmedetomidine for awake carotid endarterectomy:efficacy,hemodynamic profile,and side effects.J Neurosurg.Anesthesiol,2004,16(2):126-135.
  • 7徐加刚,张月明,王绍明,李衍森,辛秀英.舒芬太尼和芬太尼对患者气管插管心血管反应抑制效应的比较[J].中华麻醉学杂志,2007,27(8):765-766. 被引量:58

共引文献177

同被引文献29

  • 1吴新民,许幸,王俊科,王鲲鹏,薛张纲,缪长虹,邓小明,艾登斌,于浩.静脉注射右美托咪啶辅助全身麻醉的有效性和安全性[J].中华麻醉学杂志,2007,27(9):773-776. 被引量:242
  • 2Ballard C,Jones E,Gauge N,et al.Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery,a randomised controlled trial[J].PLoS One,2012,7(6):e37410.
  • 3Lorenzl S,Füsgen I,Noachtar S.Acute confusional States in the elderly-diagnosis and Treatment[J].Dtsch Arztebl Int,2012,109(21):391-399.
  • 4Steinmetz J,Christensen KB,Lund T,et al.Long-term Consequences of Postoperative Cognitive Dysfunction[J].Anesthesiology 2009,110:548-555.
  • 5Nance DM,Sanders VM.Autonomic innervation and regulation of the immune system (1987-2007)[J].Brain Behav Immun,2007,21(6):736-845.
  • 6Khan ZP,Ferguson CN,Jones RM.alpha-2 and imidazoline receptor agonists.Their pharmacology and therapeutic role[J].Anaesthesia,1999,54(2):146-165.
  • 7Devlin JW,Al-Qadhee NS,Skrobik Y.Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalized patients:A review of data from prospective,randomised studies[J].Best Pract Res Clin Anaesthesiol,2012,26(3):289-309.
  • 8Nance DM,Sanders VM.Autonomic innervation and regulation of the immune system (1987-2007)[J].Brain Behav Immun,2007,21(6):736-745.
  • 9Yang CL,Tsai PS,Huang CJ.Effects of dexmedetomidine on regulating pulmonary inflammation in a rat model of ventilator-induced lung injury[J].Acta Anaesthesiol Taiwan,2008,46(4):151-159.
  • 10Nishina K,Akamatsu H,Mikawa K,et al.The effects of clonidine and dexmedetomidine on human neutrophil functions[J].Anesth Analg,1999,88(2):452-458.

引证文献3

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部