主动脉脉压与冠心病患者冠状动脉损害程度的相关性

Relationgship between pulse pressure and severity of coronary artery disease

目的探讨主动脉脉压与冠状动脉病变严重程度的相关性。方法拟诊冠心病或确诊冠心病的住院患者340例,按病变累及冠状动脉支数分为冠状动脉正常对照组(120例)、单支病变组(78例)、双支病变组(66例)和3支病变组(76例)。冠状动脉损害程度采用Gensini积分法。比较各组的主动脉脉压与冠状动脉狭窄程度的关系。结果三支病变组的主动脉脉压高于对照组,多因素分析结果显示,主动脉脉压与冠状动脉狭窄程度的关系最为密切。结论脉压是冠状动脉狭窄发生发展的独立危险因素,且主动脉脉压的预测价值更大。

Objective To evaluate the relationship between pulse pressure（PP） and the severity of coronary artery stenosis.Methods Three hundred and forty patients who were suspected or diagnosed as coronary artery disease were enrolled.They were divided into normal control group（120 cases）,single-vessel lesion group（78 cases）,doublevessel lesion group（66 cases） and triple-vessel lesion group（76 cases） according to the number of diseased arteries.And the severity of coronary artery stenosis was evaluated by Gensini score.To compare the relationship of aortic pulse pressure and the severity of coronary artery stenosis among the four groups.Results The aortic pulse pressure was significantly higher in patients with coronary artery disease than that in the normal subjects.Multiple regression analysis indicated that aortic pulse pressure was closely related to the severity of coronary lesions.Conclusion Pulse pressure is an independent risk factor for the severity of coronary artery stenosis,and aotic pulse pressure is a better predictor.