摘要
目的探讨逍遥散防治酒精性肝病的机理。方法建立大鼠酒精性肝病模型,随机分为空白对照组、模型对照组、逍遥散治疗组。给药后观察药物对模型大鼠血清生化指标的影响。结果逍遥散可降低酒精性肝病大鼠血清乙醇脱氢酶(ADH)和谷光苷肽-S转移酶(GST)活性。结论逍遥散对酒精性肝病大鼠肝脏有明显保护作用。
Objective To analyze mechanism of xiao-yao powder treating alcoholic hepatic diseases. Methods Es- tablishing the model of alcohol liver injury rats, then dividing rats into 3 groups, contrast blank group,contrast model group,xiao-yao powder treated group. Observing influence of xiao-yao powder on serum biochemical indexes of model rats after having treated. Results Xiao-yao powder can decreasing activation of ADH,GST in serum of alcohol liver injury rats. Conclusion Xiao-yao powder shows significantly protecting effect on liver of alcohol liver injury rats.
出处
《辽宁医学杂志》
2013年第3期111-112,共2页
Medical Journal of Liaoning
基金
辽宁省教育厅科学技术研究项目(项目编号:2009A487)
关键词
逍遥散
酒精性肝损伤
肝功能
动物实验
xiao-yao powder alcoholic hepatic diseases liver function experimental study
