柴胡疏肝散治疗脑卒中后抑郁临床疗效观察

Clinical Effect Observation on Post-stroke Deprsssion Treated with Chaihu Shugan Powder

[目的]观察柴胡疏肝散治疗脑卒中后抑郁的疗效。[方法]将102例脑卒中后抑郁患者随机分成两组,治疗组52例予柴胡疏肝散和氟哌噻吨美利曲辛治疗,对照组50例予氟哌噻吨美利曲辛治疗,2周为1疗程,连续治疗4疗程,采用汉密尔顿抑郁量表于治疗前及治疗第2、4、8周末评定疗效。[结果]治疗前2组抑郁评分差异无统计学意义(P>0.05),治疗2、4、8周后2组抑郁评分组间差异有统计学意义(P<0.05);治疗组疗效明显优于对照组(P<0.05)。[结论]柴胡疏肝散是治疗脑卒中后抑郁的一种有效治疗方法。

[Objective] To evaluate the clinical effect of Chaihu Shugan Powder on Post-stroke Depression.[Methods] 102 cases of Post-stroke Depression were randomly divided into two groups.The teatment group（n=52） using Chaihu Shugan Powder combined with Flupenthixol melitracen,while the control group（n=50） with Flupenthixol melitracen.Two weeks was considered a course of treatment and all cases were given continuous three courses of treatment.The therapeutic effect was measured by HAMD depression measuring scale tests before treatment and at the end of 2th,4th,8th treatment cycle.[Results] HAMD scores of two groups had no statistical significance before treatment,but had statistical significance after 2th,4th,8th weeks’ treatment.The effect of treatment group was better than the control group.[Conclusion] Chaihu Shugan Powder is an effective method of treatment for Post-stroke Depression.