火器伤早期狗肺内血小板扣压的变化及其对纳络芬治疗的反应

Changes of pulmonary platelet trapping and their reaction to nalorphine in the early stage of gunshot injury in dogs

本文报告用7.62mm,1.03g钢珠射击狗双后肢8 h狗肺血小板扣压(简称PPT)的变化及其对纳络芬(Nalorphine)治疗的反应。结果表明,伤后8h,狗PPT明显增加(P<0.01)。当伤前、伤后连续给予Nalorphine治疗后,创伤狗PPT明显降低(P<0.01)。提示:高速投射物伤早期,狗PPT增加与创伤引起的鸦片μ受体激活有关。

The changes of pulmonary platelet trapping (PPT) were observed in dogs after they were traumatized with steel-sphere shooting and then the therapeutic effects of nalorphine were studied.It was found that the PPT rate was significantly increased in the 8th hour after injury;when nalorphine was administered before and after gunshot wounding,the PPT rate of the traumatized dogs was signficantly lowered.The fact indicates that the increase of PPT rate in the gunshot dogs results from the activation of opiate μ receptor in the lungs.